A fault determination system of a button-type shifter is provided. The system maximally guarantees the operation of a shift button while determining a failure of the shift button and improves reliability and fault diagnosis performance for the shift button. The system includes a base that is installed within a vehicle and includes shift buttons and contact points for each of the shift buttons. A controller receives contact signals from the contact points to thus determine a failure of the shift button when any one of the contact points is not sensed or is stuck when the shift button is engaged.