The invention discloses an organic light emitting diode display panel and a manufacturing method therefor, and a display apparatus. The display panel comprises a plurality of display devices which are arranged on a display region of a substrate, at least one retaining wall structure which is arranged on the peripheral region of the substrate and around the multiple display devices, an encapsulation film which is used for at least covering the multiple display devices, a barrier film which is arranged on the encapsulation film, and a bonding layer which is arranged between the encapsulation film and the barrier film in a filling way. By setting the thickness of a region, relative to the at least one retaining wall structure, of the barrier film to be greater than that of a region, relative to the multiple display devices, of the barrier film, the thickness of the barrier film with relatively strong water and oxygen blocking capability in the region of the retaining wall structure is improved, so that water vapor and oxygen cannot enter the interior of the display panel from the bonding layer on the side surface of the display panel easily, and the water and oxygen blocking capability of the side surface of the display panel can be improved.