The invention belongs to the field of an electronic product, and specifically relates to an energy-saving and collision-resisting mouse. A cover plate is fixed on a base through a screw; a laser hole is formed in the cover plate; an air inlet valve is arranged on the right side of the base; the cover plate and the base are fixed to form a left hollow cavity and a right hollow cavity; a control circuit board is fixed in the left hollow cavity; the control circuit board is provided with a Bluetooth module; a lithium battery and a rectifying and filtering circuit are embedded in the right hollow cavity; a pressure sensor is mounted on the upper part of the base; an opening sealing edge of a silica gel body is pasted on the base, and the surface of the silica gel body is arc-shaped; a touch plate is pasted on the left side of the silica gel body along the arc-shaped surface; a PVDF film is pasted on the inner surface of the silica gel body; and the outer surface of the silica gel body is coated with an antilubricant. According to the mouse provided by the invention, an internal power generation apparatus is adopted to charge the battery, so that the mouse is energy-saving and environment friendly; and the interior of the mouse is inflated, so that the mouse can be matched with palm shapes of different users, and the mouse is relatively high in collision resistance.