The invention discloses a device and method for cutting seam cartridge underwater explosion test experiments. The device comprises a first horizontal support frame telescopic leg (5), a second horizontal support frame telescopic leg (8), at least one first rotating support frame telescopic leg (6) and at least one second rotating support frame telescopic leg (7), wherein a probe for performing sensing measurement on the explosion test process is arranged on each of the first horizontal support frame telescopic leg (5), the second horizontal support frame telescopic leg (8), the first rotating support frame telescopic leg (6) and the second rotating support frame telescopic leg (7); the distance between the first horizontal support frame telescopic leg (5) and the second horizontal support frame telescopic leg (8) can be adjusted; the distance between the first rotating support frame telescopic leg (6) and the second rotating support frame telescopic leg (7) can be adjusted, so that the explosion performance in different space positions around a cutting seam cartridge is measured; high flexibility is realized; different experimental requirements can be met.