The invention provides a verification method and device for data information consistency between a master station and a substation. The method comprises the steps that a substation data information test sequence is constructed according to a master station demand data information sheet and a substation SCD file; data information in the substation data information test sequence is obtained as testing data, and the testing data is stored in a test state mode; data information in the master station demand data information sheet is compared with the testing data, and if the data information in the master station demand information sheet is consistent with the content and the sorting sequence of the testing data, it is determined that data information between the master station and the substation has consistency. By adopting data information analysis configuration and the comparison and emulation technology, consistency of the substation data and the master station data is flexibly verified. According to different verified objects and stages, the data verification efficiency is improved by adopting automatic or manual or incremental information verification schemes, the on-site equipment power-off time is shortened, and therefore the on-site working efficiency is improved.