The invention relates to an intelligent power distribution network fault detection device based on a packet transport network and a wireless network. The intelligent power distribution network fault detection device includes a management module, an acquisition module, a differential protection module, a measurement control module and an information interaction and time synchronization terminal; the differential protection module is used for receiving SV data and goose data to execute a distributed differential protection logic function and exchanging CAN network data and internal Ethernet data with the management module; and the measurement control module includes a time synchronization unit, an information acquisition unit and a control unit and can realize a time synchronization function, exchanges the SV data and goose data with adjacent device, receives an INI file sent by the management module through an inner protocol and based on an inner bus so as to exchange management information with the management module, and exchanges data with the differential protection module through an internal 50M bi-directional port. According to the device of the invention, a master-slave clock scheme is adopted; time is encoded and transported; and the synchronization of the frequencies, phases and absolute time of a master clock and a slave clock is realized through using the symmetry of network links and delay measurement technologies.