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发明授权
CN106924278B 一种蓬蘽花色苷及其用途 有权

一种蓬蘽花色苷及其用途
摘要：
本发明公开了一种蓬蘽花色苷及其用途。蓬蘽花色苷主要包括矢车菊素‑3‑O‑葡萄糖苷、天竺葵素‑3‑O‑葡萄糖苷和天竺葵素‑3‑O‑芸香糖苷，其中天竺葵素‑3‑O‑葡萄糖苷为主要花色苷。经动物实验证明，蓬蘽花色苷能显著降低db/db糖尿病小鼠的空腹血糖，在体内展现出优良的降糖活性。体外实验证明蓬蘽花色苷能够通过抑制α‑葡萄糖苷酶活性和促进细胞对葡萄糖的消耗而起到降糖作用。因此，蓬蘽花色苷可作为降糖功能食品或降糖药物用于糖代谢异常相关疾病的防治，本发明为综合开发利用我国蓬蘽资源提供新的思路。
摘要（英）：

The invention discloses rubus hirsutus anthocyanin and application thereof. The rubus hirsutus anthocyanin mainly comprises cyanidin-3-O-glucoside, pelargonine 3-O-glucoside and pelargonine 3-O-rutinoside, wherein the pelargonine 3-O-glucoside is main anthocyanin. An animal experiment proves that the rubus hirsutus anthocyanin can significantly reduce fasting blood glucose of db/db diabetic mice and shows excellent hypoglycemic activity in vivo. An in-vitro experiment proves that the rubus hirsutus anthocyanin can play a hypoglycemic role by inhibiting the alpha-glucosidase activity and promoting the glucose consumption of cells. Therefore, the rubus hirsutus anthocyanin can be taken as hypoglycemic functional food or a hypoglycemic drug for the prevention and the treatment of glycometabolism disorder-related diseases. The invention provides a new idea for comprehensive development and utilization of rubus hirsutus resources in China.

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