The invention discloses a safety control system and method based on the V2V communication charging process. The safety control system comprises a GPS module, a panorama system module, a V2V communication unit, a CAN bus communication unit and a central processor. The holographic system measures the relative positions between a charging vehicle and charged vehicles. The CAN bus communication unit obtains the charging state of a charging gun and the vehicle model information of the charged vehicles and is also used for cutting all charging connecting devices, opening an alarm lamp and informing all the charged vehicles to be driven away. The central processor obtains the positioning information of the charging vehicle, calculates the information of the charged vehicles, and is also used for obtaining the vehicle information collected by the V2V communication unit in the nearby non-service range and judging whether the vehicle running trajectory in the non-service range penetrates through the service range of the charging vehicle or not. According to the safety control system and method based on the V2V communication charging process, collision accidents might occurring between the movable charging vehicle and nearby other running vehicles as well as between the charged vehicles and the nearby other running vehicles are avoided in the charging process, and the safety failures or hidden dangers might caused by collision are reduced.