The invention relates to the field of a wet magnetic plant, and discloses a high-frequency harmonic magnetic field cleaning magnetic separator. The high-frequency harmonic magnetic field cleaning magnetic separator comprises a separation barrel, a groove body, an ore feeding box, an ore discharging device and a concentrate collecting device; a magnetic system is arranged in the separation barrel and is singly driven by a magnetic system driving device to rotate; the groove body is arranged at the lower portion of the separation barrel and is sequentially provided with a separation zone, a flow stabilization zone, a rinsing zone and a concentrate rinsing device in the rotating direction of the separation barrel, and the bottom of the separation barrel is located below a separation liquid level of the groove body; the ore feeding box is communicated with the separation zone through a pipe and is used for conveying ore to the separation zone; the ore discharging device is located in the first quartile of the separation barrel, and is composed of a mechanical forced shoveling device and an induction forced discharge device; and the concentrate collecting device is fixed to the groove body and is used for collecting concentrate obtained after ore discharging. By means of the high-frequency harmonic magnetic field cleaning magnetic separator, the concentrate mixing problem can be effectively solved, and the concentrate grade is improved.