The invention provides an isolation management system for smart devices and a use method therefor. The isolation management system performs simple and convenient isolation to power distribution equipment through a first lock unit, a second lock unit, an authorization unit, a first reading unit, a second reading unit, a collection unit, a display unit, a first input unit, a second input unit, and a control unit. The isolation management system brings convenience to maintenance of power distribution equipment and can be associated with an information system, thereby brining convenience to maintenance and management.