The invention discloses a magnetism guided reduction and fixation device for orthopedic surgery. The device comprises a reduction tong body and a guide structure, wherein the guide structure comprises guide apparatus and a magnetic metal ball I; the guide apparatus comprises a guide ball, spherical fixing shells, a positioning pin, a locking bolt and a guide pipe, and the guide ball can freely rotate relative to the central axes of the spherical fixing shells at very low friction force; the positioning pin and the locking bolt can position and lock the guide ball. By means of the technical scheme, a screw can be accurately implanted in orthopedic surgery of some parts in a minimally invasive manner, and repeated, tentative and temporary fixation and excessive X ray irradiation to a patient are avoided; the guide structure in the technical scheme has the advantages of being accurate in guide and simple, convenient and stable to position.