The invention discloses a solid-liquid circulatory separation device for chemical experiments, which comprises a tank, water pumps, and a filter system, the filter system comprises a buffer tank, a sloped tank, a negative pressure chamber, and a return gas chamber, the bottom of the sloped tank communicates with the negative pressure chamber, and the negative pressure chamber communicates with a clean water reservoir through an output pipeline, the middle of the inclined bottom of the sloped tank is provided with a sloped leakage hole, a first filter screen is arranged at a position downstream from the sloped leakage hole, and a sludge discharge passage is arranged under the sloped leakage hole. Through the two stages of water pumps, the solid-liquid circulatory separation device for chemical experiments can implement two types of operating modes, and the different operating modes are chosen according to the requirements of components of chemical sewages needing to be treated. Under the condition of not causing blockage and not affecting working efficiency, three sets of filter screens at different positions can carry out filtration and sewage discharge to the max, so that wastewater discharge can come up to the standard.