The invention discloses a making method of an internal supporting vacuum glass body. The making method comprises the following steps that materials are selected, and two glass plates, two cover plates, two end plates and multiple supporting plates are selected; the end plates are processed, installing holes are formed in the end plates, two sides of each end plate are bent toward one side after the installing holes are formed, so that end plates respectively provided with two folded plates are formed; supporting plates are installed, and the two end plates are oppositely arranged; two ends of each supporting plate are respectively inserted into the installing holes corresponding to the two end plates; after the supporting plates are installed, an adhesive is applied in the installing holes for fixing; assembly is performed, the two glass plates are connected with the folded plates of the two end plates, the two cover plates respectively cover the upper and lower ends of the two glass plates and the two end plates; sealing treatment is conducted on connecting position; punching is performed, wherein the glass plates or the end plates are punched for vacuumizing. Due to the fact that the making method includes simple and easy process steps and is low in cost, the internal supporting vacuum glass body can be widely used.