The invention discloses an infusion device capable of mixing liquid in real time. The infusion device comprises a motor provided with a rotating output shaft, the rotating output shaft is connected with a supporting base, and the supporting base is connected with an infusion bottle; a lower inner conducting ring, an upper inner conducting ring, a lower outer conducting ring and an upper outer conducting ring are arranged outside the infusion bottle and connected with an end ring plate through the supporting base, an inner conducting column is connected between the lower inner conducting ring and the upper inner conducting ring, an outer conducting column is connected between the lower outer conducting ring and the upper outer conducting ring, the lower inner conducting ring is connected with a first input wire through an inner sliding conducting piece, a first output wire is fixed at the upper end of the inner conducting column, the lower outer conducting ring is connected with a second input wire through an outer sliding conducting piece, and a second output wire is fixed to the upper end of the outer conducting column; a through hole in the vertical direction is formed in the central axis of the rotating output shaft, the lower end of the infusion bottle is communicated with an infusion pipe, and the infusion pipe vertically stretches out of the through hole of the rotating output shaft to the outside; the infusion bottle can be continuously rotated in real time, and the purposes of real-time liquid mixing and infusion are achieved.