A method of acquiring a probability static state voltage stabilization margin based on Quasi monte carlo simulation and kernel density estimation is disclosed. The method comprises the following steps of according to power grid data, carrying out pretreatment to acquire an input random variable matrix; and then using a diffusion-based kernel density method (DKDM) to acquire a probability density of a voltage stabilization margin and cumulative probability distribution. In the invention, through introducing the Quasi monte carlo simulation, an input random variable sample is acquired so as to increase calculating efficiency of a simulation method; the diffusion-based kernel density method is used to accurately acquire a probability distribution function of the stabilization margin; and only a small sampling scale is needed and high calculating precision can be acquired.