The invention discloses a time sequence controller. The time sequence controller comprises a first digital gamma correction unit, a second digital gamma correction unit, and a micro-control unit. The micro-control unit is used to count output frames after receiving a video signal, and is used to determine whether polarity reversal of a pixel digital voltage of a current frame is required according to a counted number. When the polarity reversal of the current frame is required, a first digital gamma correction table read from the first digital gamma correction unit is used to calculate the pixel digital voltage. When the polarity reversal of the current frame is not required, a second digital gamma correction table read from the second digital gamma correction unit is used to calculate the pixel digital voltage. The calculated pixel digital voltage is output to a display module used to display the video signal. A problem of periodic flickering during occurrence of polarity non-reversal frames is solved.