The invention discloses a method for screening out an inherited metabolic disease of a newborn. The method comprises the steps of storing disease condition symptom data and index data of existing inherited metabolic disease in a database, and establishing a medical database according to the database; collecting a detection sample of the newborn, and importing the detection sample into the medical database; and comparing the detection sample with the index data in the medical database, and judging whether the detection sample is matched with the index data in the medical database or not. By performing comparative matching on the detection sample of the newborn and the existing data in the established medical database, the inherited metabolic disease related to the newborn can be quickly screened out and an examination report in a text format is generated; and the data can assist in diagnosis of doctors, so that the misdiagnosis rate of the doctors is reduced, the diagnosis efficiency of the doctors is improved, and a diagnosis result is more accurate.