The invention discloses a hierarchical multi-level grid regulation method for a large-scale building load cluster. The method comprises: a grid dispatching terminal decomposes a control task and distributes the decomposed units to all distribution network zone dispatching terminals; all distribution network zone dispatching terminals regulate and control controlled building clusters respectively; all large buildings serving as basic nodes coordinate internal demand side resources; and a flexible resource aggregation side exploits a demand response potential of each building load and transforms lots of dispersed demand side resources with low capacities into flexible resources capable of providing energy services for a flexible resource using side based on an aggregation algorithm. The hierarchical multi-level grid regulation method has advantages: complexity of regulation and control is reduced; and the grid load tracking power capacity of a metropolitan received terminal is maximized.