The invention discloses a one-button type gelatin liquidation system. The system comprises a PLC, a vacuum system, a pressure transmitter, a pressurizing system, a breathing valve, a foam detector, a temperature transmitter, a hot water system, a pressure switch, a frequency converter, a mixing system, a weight transmitter, a CIP valve, a discharging valve, a feeding valve, a gelatin liquidation tank, a pneumatic valve and control software. The weight transmitter transmits the on-line weight to the PLC, and the feeding valve and the discharging valve are controlled by the PLC; the temperature transmitter transmits the material temperature to the PLC, and water supply and stop of the hot water system are controlled by the PLC; the pressure in the gelatin liquidation tank is transmitted to the PLC through the pressure transmitter, and the PLC controls the vacuum system, the pressurizing system and the breathing valve; the foam detector transmits a BOOL type bubble position signal to the PLC, and the breathing valve and the vacuum system are controlled by the PLC; the pressure switch transmits the BOOL type signal to the PLC, and the PLC judges whether a command of execution of the pneumatic valve action is run or interrupted; and the frequency converter transmits the signal to the PLC, and the PLC controls the mixing system through the frequency converter.