A patch is provided (1) able to produce micro-current to be applied on human skin comprising a support for electrodes (3a, 3b) spaced from each other and apt to create voltages typical of galvanic piles, connection means (5) between the electrodes (3a, 3b), an adhesive layer (4) applied on one side of the support and apt to adhere to the skin and a protection liner (7) applied on the adhesive layer (4), the support being a membrane (2) permeable to the moisture inside the electrodes (3a, 3b), and the connection means (5) being defined by a material that is avid of moisture, such as silica impregnating the membrane (2).