The invention discloses medical devices and configuration update management. A configuration management resource keeps track of incremental updates to a locally stored copy of configuration information (such as drug library information) used by a medical device to administer treatment to patients. The medical device retrieves a copy of the configuration information from a configuration management resource. Unbeknownst to a user of the medical device, to ensure that the medical device has most up-to-date configuration information, the medical device communicates a request for updates to the configuration management resource. To service the received request for updated configuration information, the configuration management resource forwards incrementally available configuration update information to the requesting medical device. The medical device uses the received configuration update information from the configuration management resource to update its local version of configuration information stored in the medical device.