The invention discloses an automatic drug selling machine. The automatic drug selling machine comprises a box body, storage units, propelling mechanisms and a receiving table, wherein a man-machine interaction device is further arranged outside the box body. The automatic drug selling machine further comprises two storage modules which are stacked right up and down, wherein each storage module comprises at least two storage units arranged side by side; the storage units of the storage modules at the upper layer and the lower layer are stacked right up and down in a one-to-one correspondence manner; and each storage unit comprises a storage box of a hollow structure; each storage box is divided into nine cells in Sudoku distribution through partitions, the cell in the center forms a conveying channel, the other eight cells form storage cells, a discharge opening communicated with the conveying channel is formed in the bottom of each storage cell, a propelling opening allowing a propelling block to extend and move therein is formed in each storage cell, the propelling blocks extend into the propelling openings and push drugs in the storage cells into the conveying channel, and the drugs finally fall onto the receiving table, so that the drugs can be directly taken from the receiving table. Therefore, the automatic drug selling machine is not only novel in structural design but also high in storage capacity and can store various drugs.