The invention discloses a large-inclination large-mining-depth hydraulic support withdrawal system and method and belongs to the field of mining machinery. The system comprises a transfer apparatus and a support structure arranged in a withdrawal passage; the support structure comprises reinforced joists, metal mesh, anchor ropes and threaded anchor bolts which are arranged on the roof and sidewall of the withdrawal passage where hydraulic supports are arranged; support apparatuses include rails, a winch, a withdrawal platform, a withdrawal forklift and the like which are arranged in the withdrawal passage. The large-inclination large-mining-depth hydraulic support withdrawal system and method has the advantages that the reinforced joists and metal mesh are arranged on the roof and sidewall of the withdrawal passage for the purpose of blocking, the anchor ropes and threaded anchor bolts are used for fastening and supporting, the stability of the withdrawal passage in the withdrawal process of the hydraulic supports is guaranteed, and chances for gangue fleeing, roof caving and other incidents to occur are slimmed; orderly withdrawal is carried out via the step of withdrawing while supporting and reinforcing, withdrawal efficiency and quality are greatly improved, and labor intensity and cost are decreased.