This laser processing machine, which processes a work piece mounted on a table (108) by irradiating the work piece with a laser light, is provided with: an optical head (10) having a nozzle (26b) that sprays a liquid to form a columnar liquid flow and introducing a laser light into the nozzle (26a) and shining said light; and an alignment adjustment device (40) having a reflector (42) that is disposed so as to face the optical head (10) and reflects the laser light, and a light-shielding portion (34) around the portion of the reflector (42) that reflects the laser light, and adjusting the position or orientation of introduction of the laser light into the columnar liquid flow (60).