Systems and methods for operating network slices in a communication network such as a 5th generation wireless communication network are provided. Mobile device attach requests can be handled in which an appropriate network slice is selected for attaching the mobile device to. Customer service requests can be handled using existing network slices or by instantiating new network slices as needed. Mobile devices can be associated to new network slices due to roaming. Network slices can be monitored and scaled as required to maintain performance. Cloud resource assignment, mobile device power management, traffic engineering and flow management operations are also disclosed.