The invention discloses a method and device for controlling a power liftgate of a vehicle and belongs to the technical field of electronics. The method comprises the steps that a first voice signal input by a user is obtained; according to the first voice signal, a datum voice signal matched with the first voice signal is selected from a datum voice signal set; according to the datum voice signal, a control command corresponding to the datum voice signal is obtained from a correspondence relation between the datum voice signal and the control command, and the control command is an opening command or a closing command; and according to the control command, the power liftgate of the vehicle is controlled. When controlling the power liftgate of the vehicle, the user can control the power liftgate of the vehicle by directly outputting the first voice signal, the power liftgate of the vehicle can be controlled without triggering a control button manually, and accordingly the power liftgate controlling efficiency is improved.