The invention discloses a fiber distribution case comprising a case body, a case door capable of being opened or closed relative to the case body, a plurality of blast pipes arranged in the case body, a main air hose arranged in the case body, a plurality of fiber distribution racks arranged in the case body, and a plurality of wire through structures. An air outlet and a plurality of air inlets are formed in the side wall of the case body; a filter netted gauze layer is arranged at the air outlet; and filter netted gauze layers are arranged at the air inlets. The blast pipes correspond to the air inlets one by one; the inlet ends of the blast pipes are communicated with the corresponding air inlets; air-intake fans are arranged in the blast pipes; and air-intake one-way valves are arranged at the blast pipes. The outlet ends of the blast pipes are communicated with one end of the main air hose. The fiber distribution racks are provided with a plurality of wiring plugging ports for plugging of fiber joints. The wire through structures include wire through holes and elastic plugs. The fiber distribution case has the following beneficial effects: the structure is reasonable; fiber distribution switching can be carried out effectively; the heat radiation performance is good; dustproof protection can be carried out; and entrance of external dust into the inside of the case can be prevented.