The invention provides a two-section degreasing method of powder injection molding. The two-section degreasing method comprises a low-temperature degreasing section and a high-temperature reinforcing section; the temperature of the low-temperature degreasing section is 40-145 DEG C; the temperature of the high-temperature reinforcing section is 150-200 DEG C; the front-section low-temperature degreasing section can improve the degreasing efficiency and reduce cracks caused by the molding stress; and the back-section high-temperature reinforcing section can improve the degreased blank strength and the sintering density to facilitate reduction of such defects as recesses, material shortage and scratch caused by collision in the transportation process. The two-section degreasing method of powder injection molding is applied to a powder injection molding process, facilitates prolonging of the storage time of degreased blanks, and is convenient in long-distance transportation; and the two-section degreasing method facilitates production of parts with complicated structures, excellent performances and high precision requirements, and widens the application of powder injection molding.