The invention belongs to the technical field of mud resistance of compound polycarboxylate superplasticizers and discloses a mud-resistant polycarboxylate superplasticizer, a preparation method of the polycarboxylate superplasticizer as well as application in concrete, particularly application in mud-containing neat paste. The superplasticizer disclosed by the invention is a complex composed of 100 mass parts of a polycarboxylate superplasticizer and 0.01-5 mass parts of a quaternized lignosulfonate mud-resistant sacrificial agent. The quaternized lignosulfonate mud-resistant sacrificial agent is prepared by the following steps: adding a quaternization reagent and alkali into an alkaline lignosulfonate solution, heating, reacting, thereby obtaining the quaternized lignosulfonate. The superplasticizer disclosed by the invention can obviously improve the liquidity of the mud-containing neat paste, such as slump degree or divergence, has obvious mud resistance, is excellent in dispersing performance and low in cost and can be applied to the field of concrete. Synergistic effects can be achieved between the quaternized lignosulfonate mud-resistant sacrificial agent and polycarboxylic acid, and under the same doping amount, the product added with the sacrificial agent has excellent dispersing performance.