The invention discloses dry freon and protogenetic seawater heat exchange equipment which comprises an upper panel. Side baffles are fixedly connected to the two sides of the front end of the bottom of the upper panel and the two sides of the back end of the bottom of the upper panel, middle connecting plates are fixedly connected to the center position of the front end of the bottom of the upper panel and the center position of the back end of the bottom of the upper panel, and the two sides of each middle connecting plate are fixedly connected with the side baffles located on the two sides of the same end of the upper panel correspondingly; and the ends, far away from the bottom of the upper panel, of the four side baffles are fixedly connected through a lower panel, and the top of the lower panel is fixedly connected with the ends, far away from the bottom of the upper panel, of the two middle connecting plates. According to the dry freon and protogenetic seawater heat exchange equipment, the manner of direct heat exchange between protogenetic seawater and Freon is adopted, the middle heat exchange link is omitted, the seawater utilization temperature can be increased by more than 3 DEG C, the heat energy using rate can be improved by about 10%, and therefore the effects of simplifying protogenetic seawater source using equipment and improving the protogenetic seawater source heat energy using efficiency are improved.