The invention discloses a safety unlocking method for an intelligent lock system. A center control mobile phone and an intelligent lock are subjected to primary binding; intelligent lock identification information of the bound intelligent lock is stored by the center control mobile phone; mobile phone identification information of the bound center control mobile phone is stored by the intelligent lock; the center control mobile phone independently generates an unlocking password according to the mobile phone identification information and the stored intelligent lock identification information; and the intelligent lock independently generates a password in the lock according to the stored mobile phone identification information and the intelligent lock identification information of the intelligent lock. During unlocking, the unlocking password generated by the center control mobile phone is input into the intelligent lock, and the unlocking password and the generated password in the lock are subjected to comparison validation by the intelligent lock; if the unlocking password is the same as the password in the lock, the intelligent lock is unlocked; and if the unlocking password is different from the password in the lock, the intelligent lock is continuously locked. According to the safety unlocking method provided by the invention, the whole process is initiated and used by an actual user, a third-party platform does not need to participate in, the unlocking safety and reliability are guaranteed, and the personal safety and property safety of the user are guaranteed.