The invention discloses a smoke dust and paint mist treatment process which is optimized aiming at problems of poor effects, high cost and low efficiency in existing paint mist treatment. The method includes steps: primary absorption of smoke dust and paint mist; dewatering and dedusting; further treatment of smoke dust and paint mist; discharging. A three-layer filter device is used for further filtration, a first layer is a moisture layer, and adverse effects of moisture on a smoke dust adsorption layer are avoided due to earlier absorption of moisture in an adsorption tower; various drying water absorbents are adopted to adapt to various places; by activated carbon for adsorption of large particles in paint mist, the paint mist can be further filtered, and recycling of the activated carbon is realized; by synergy of low-temperature plasmas and an integral photocatalysis machine for paint mist degradation, paint mist can be ionized into ozone, water, carbon dioxide and other nontoxic gases by plasma discharging, and ozone which is high in corrosion is converted into oxygen by photocatalysis.