The invention relates to a soluble micro-pin patch and a preparation method thereof. The pin point of the micro-pin patch is prepared from, by weight, 7-14 parts of hyaluronic acid or salts thereof, 0.05-0.2 part of functional active ingredients, and 6-11 parts of shaped materials; the hyaluronic acid or salts thereof are mixtures of low molecular weight hyaluronic acid or salts thereof and high molecular weight hyaluronic acid or salts thereof, wherein the molecular weight of the small molecular weight hyaluronic acid or salts thereof is less than 10 kDa, the molecular weight of the high molecular weight hyaluronic acid or salts thereof is not less than 1800 kDa; the functional active ingredients are selected from oligo-peptide-1, oligopeptide-3, hydrolyzed collagen, and at least one of the hyaluronic acid or salts thereof; the shaped materials are selected from polyvinyl alcohol and derivatives thereof, polyvinyl pyrrolidone and derivatives thereof, and at least one of lactose, sorbitol, dextran, trehalose and sucrose. The soluble micro-pin patch has the properties of good rigidity and strength.