The invention relates to the field of a chemical industrial device, specifically to an anti-clogging reaction vessel. The reaction vessel includes a vessel body; a cover is mounted on the top of the vessel; a stirring mechanism is mounted on the cover; a filter screen adapted to a cross-section of the vessel body is mounted at the lower part of a stirring shaft; a gravity inductor is mounted at an edge of the filter screen; a vibrating component is arranged at the lower part of the gravity inductor and comprises a mounting base and a vibrator, which is internally provided with a circuit board, wherein the circuit board is in electrical connection to the gravity inductor; and the lower part of the vessel body is provided with a discharge port, which is provided with a hemispheric filtering blocking screen and is covered with a heating belt. The vessel is simple in structure and convenient to operate, prevents the phenomenon of super difficult movement of materials in the vessel, reduces large blocks in the materials, and can prevent the phenomenon that the discharge port is clogged due to temperature variation.