The invention relates to an energy station configuration method in a regional energy plan and design stage. The method comprises the following steps of: carrying out analog calculation in cooling and heating electric loads of buildings in a region to obtain regional load characteristics; obtaining primary energy technologies according to geographic, resource and meteorological characteristics in the region and the regional load characteristics; obtaining basic parameters and an energy cost of technical equipment corresponding to each primary energy technology; establishing a regional energy station configuration model, wherein the model considers the production cost of energy, the operation and maintenance costs, the cost change of daytime energy consumption, a market free transaction mechanism, a cold and heat accumulation, carbon emission tax rate and the change of equipment efficiencies along with operation states; and solving the regional energy station configuration model by using a branch cutting algorithm, and obtaining an energy technology category and a corresponding configuration capacity. Compared with the prior art, the method is capable of solving the problems of energy station energy technology category selection and corresponding equipment capacity configuration in the regional energy plan and design stage, and has the advantage of being high in reliability.