The invention relates to a system and method for optoelectronic information time domain-related non-invasive blood parameter monitoring. A light source array is disposed on one side of a monitored part, a non-blocked light field area of the monitored part is provided with a non-photoelectric sensor array; a photodetection array is disposed in a light field propagation area after a light field passes the monitored part; the photodetection array detects photoelectric information containing monitored material information and converts and transmits the information to a time domain-related processing module, the time domain-related processing module transmits blood parameter monitoring-related information to a parameter extraction module; the non-photoelectric sensor array transmits collected non-photoelectric sensing information to a correction compensation module, the correction compensation module performs correction compensation on monitored parameters through the non-photoelectric sensing information, and non-invasive blood parameter data is obtained and transmitted to an information output module to be output or displayed. The system and method for optoelectronic information time domain-related non-invasive blood parameter monitoring have the advantages that the method is simple, the system is high in precision, good in consistency, rich in function, wide in applied range, high in reliability, flexibility and user experience, and functions are expanded easily.