The invention relates to a traditional Chinese medicine composition preventing postmenopausal osteoporosis. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 15 to 20 parts of epimedii folium, 5 to 10 parts of frozen-dried cervi cornu pantotrichum, 15 to 20 parts of radix astragali, 5 to 10 parts of flos carthami, 15 to 20 parts of radix rehmanniae, and 5 to 10 parts of concha ostreae, wherein the epimedii folium is a sovereign drug, the frozen-dried corn cervi pantotrichum, the radix astragali and the flos carthami are ministerial drugs, the radix rehmanniae is an adjuvant drug, and the concha ostreae is a conductant drug. The traditional Chinese medicine composition can reinforce kidney to replenish essence, benefit qi for activating blood circulation and strengthen bones and muscles, and is mainly used for treating postmenopausal osteoporosis and other secondary osteoporosis.