The invention discloses pipe cleaning equipment, and relates to the technical field of pipe cleaning. The pipe cleaning equipment comprises a chassis and a power supply; the chassis consists of a box cover and a box body; an operation panel is arranged at the upper part of the box body; an accommodating cavity is formed between the operation panel and the box body; a cleaning device is arranged in the accommodating cavity; and the cleaning device comprises a reagent cleaning device, a pulse cleaning device and a controller. The pipe cleaning equipment can perform the reagent cleaning and the pulse cleaning on pipes; the reagent cleaning adopts a green and environment-friendly high-quality food-grade cleaning agent; the open cycle is used for pre-removing limescale, bacteria and rust in the pipes firstly; then, the pulse cleaning is adopted to quickly peel off such accumulations as rust, sediments and algae on the inner walls of the pipes layer by layer, and the accumulations are discharged out of the pipes from pollution discharge pipes; and the steps are repeatedly operated to realize thorough cleaning of water supply pipes, to improve the water supply flow and to effectively purify the water supply quality. The reagent cleaning device and the pulse cleaning device are assembled in one chassis, so that the size is small, the carrying is convenient, and the operation is simple.