The invention relates to the technical field of artworks and particularly discloses a manufacturing method for a handicraft picture. The manufacturing method comprises the following steps that granular activated carbon is subjected to dust removal, impurity removal and screening treatment and mixed with diatom ooze, an environment-friendly water-soluble bonding agent is added, then a sizing agent is prepared, forming and drying treatment are conducted, and then a base of the handicraft picture is obtained; the base of the handicraft picture is uniformly coated with shaping paste to conduct shaping, and after shaping and drying, drawing is conducted through acrylic paint; or the shaping paste and the acrylic paint are mixed, and then drawing is directly conducted on the base of the handicraft picture; and the well-manufactured picture is subjected to picture mounting for package through frame strips, and then the handicraft picture is obtained. The technique is simple, and operating is convenient; according to the manufacturing method, the adsorption and purifying functions of the activated carbon and the diatom ooze are ensured, and the air permeability of the shaping paste is sufficiently utilized; and the acrylic paint has the advantages of being rapidly dry, full in color, environmentally friendly and nontoxic, so that the handicraft picture has the decorative effect and air purifying efficacy.