The invention relates to the technical field of mechanical structure design, and discloses a loading and unloading manipulator of a module detection line. The loading and unloading manipulator comprises a support plate; a mounting plate arranged on the lower surface of the support plate; a grabbing component arranged on the lower surface of the mounting plate; and a driving component arranged on the lower surface of the support plate and used for driving the mounting plate to slide in the length direction of the support plate. The loading and unloading manipulator of the module detection line has the advantages of high degree of automation, and saving of human and material resources.