The invention is applicable to the technical field of depositing and withdrawing equipment, and particularly relates to a banknote detection control method, a banknote detection control device, and depositing and withdrawing equipment. When an abnormal banknote is detected for the first time in each round of sorting process, the abnormal banknote is guided to an abnormal banknote receiving position. Whether banknotes after the abnormal banknote are abnormal banknotes is detected in turn. According to the detection result, abnormal banknotes are guided to the abnormal banknote receiving position, and non-abnormal banknotes are guided to a banknote storage area, until separated banknotes in the round of sorting process are all guided to the corresponding area or position. The sorting process is repeated multiple rounds. When banknotes deposited by a user are all detected, banknote detection is ended, and abnormal banknotes deposited by the user are returned to the user via a depositing and withdrawing mouth. It can be seen that the non-abnormal banknotes after the abnormal banknote are guided to the banknote storage area. Thus, repeated detection of non-abnormal banknotes is avoided, the number of times of banknote detection is reduced, and the efficiency of banknote detection is enhanced.