The invention discloses a substation pressure plate anti-misoperation control system, relates to the technical field of power grid operation security, and in particular belongs to an anti-misoperation control state of a substation on-site pressure plate and switching operation whole process pressure plate state. The system includes a computer, a data transmission seat, a PDA anti-misoperation key, a lock with RFID electronic tag lock code information, a microprocessor protection device, a switch and disconnector measurement and control device and a pressuring plate. The PDA anti-error key is connected with the computer through the data transmission seat. The PDA anti-error key reads out the RFID electronic tag lock code information on the lock through radio frequency technology. The pressure plate includes an upper base (11) and a lower base (12). According to the invention, the regular checking work of an on-site pressure plate by operation and maintenance personnel can be replaced, the workload and work intensity of the operation and maintenance personnel are substantially reduced, the cases in which the pressure plate is not checked due to human causes can be eliminated, and the operation and maintenance management level is effectively improved. The system of the invention has a positive effect of improving the management level of equipment and effectively managing and controlling the pressure plate by the operation and maintenance personnel.