The present invention discloses a method and device for deletion of contact person's numbers, belonging to the mobile terminal technology field. The method comprises: when detecting the operation of a target contact person adding new communication numbers, displaying a prompting pop-up window, wherein the pop-up window comprises prompting information and a first operation control; after obtaining triggering signals corresponding to the first operation control, displaying a failure time setting interface; obtaining failure time information set in the failure time setting interface, wherein the failure time information is configured to indicate the failure time of original communication numbers of the target contact person; and when the failure time is arrived, deleting the original communication numbers of the target contact person. According to the embodiment, a function of deleting the original communication numbers of the target contact person at a fixed period is extended in the mobile terminal so as to realize the simplification of the operation required by deletion of the original communication numbers of the target contact person and avoid generation of mistaken deletion.