The invention provides a processing method and device for an indication message of resource scheduling and a method and device for centralized scheduling. The processing method comprises the steps of determining a first transmission resource and a second transmission resource; determining the maximum number transmission times capable of being indicated by the indication message; determining a first indication message used for indicating the first transmission resource when the remaining number of transmission times of a first data packet is greater than or equal to the maximum number of transmission times of the indication message; determining a second indication message used for indicating the first transmission resource and the second transmission resource when the remaining number of transmission times of the first data packet is less than the maximum number of transmission times of the indication message; and transmitting the indication message and the first data packet required to be transmitted at present of a target node on the same target subframe. The processing method provided by the embodiment of the invention for the indication message enables a node to acquire further resource occupation conditions through SA decoding, and can effectively improve the efficiency of resource scheduling while reducing the cache overhead.