The invention discloses a crane hoisting mechanism capable of preventing the phenomenon of jumping from a slot. The crane hoisting mechanism comprises a hoisting mechanism body. Rope pressing roller supports are installed at the two ends of the side face of a hoisting drum correspondingly and are further fixed to a trolley frame through bolts. Short shafts are welded to the two ends of a rope pressing roller, and the two ends of the short shafts penetrate into an inner ring of a deep groove ball bearing and are fixedly connected with the rope pressing roller supports through an outer ring on the deep groove ball bearing. The diameter of the rope pressing roller is 5cm larger than that of a steel wire rope. According to the technical scheme, losses of the steel wire rope are reduced, the service life of the steel wire rope is prolonged, and the phenomenon of disorderly rope arrangement is effectively prevented.