The invention discloses a preparation method for a drug-loadable tissue repairing membrane. The drug-loadable tissue repairing membrane comprises an electrospun fibrous membrane main body, at least one hermetic drug storage chamber formed in the electrospun fibrous membrane main body and a drug storage medium arranged in the drug storage chamber, wherein the electrospun fibrous membrane main body is prepared from a hydrophobic degradable material, and the drug storage medium is prepared from a hydrophilic degradable material. According to the tissue repairing membrane in the invention, the drug storage medium is wrapped in the electrospun fibrous membrane main body, and a drug solution can be injected into the drug storage medium before usage of the tissue repairing membrane so as to realize the drug loading and sustained drug releasing functions of the tissue repairing membrane, so the tissue repairing membrane is simple and convenient to use and prevents destroy of factors like organic solvents in conventional drug loading methods to drugs; moreover, the tissue repairing membrane can realize in-situ long-term stable drug delivery during tissue repairing, does not need to take out, is simple to operate and has good clinical application value in the field of tissue repairing.