Belonging to the technical field of inclined shaft construction, the invention discloses a grouting material and a local fractured formation inclined shaft inverse well guide hole drilling technology using the same. The grouting material includes: P.O42.5 ordinary portland cement, fine aggregate, mineral powder, silica fume, an expansive agent, a water reducing agent and an anti-dispersion compound. The cement based grouting material provided by the invention can be used at an underwater bottom layer, has short setting time, high strength, strong underwater anti-dispersion ability, and a hole sealing success rate up to 95% or more. The local fractured formation inclined shaft inverse well guide hole drilling technology provided by the invention utilizes a raise boring machine drill rod to inject the cement based grouting material into a fracture zone so as to reinforce the fractured formation. The inverse well guide hole drilling technology provided by the invention can achieve construction in fractured formation, the construction efficiency can be improved by 25% or more, and also the application scope of inverse well method is broadened.