The invention provides an anti-misoperation method, apparatus and system in operation order dispatching, and belongs to the technical field of detection management of an electric power system. According to the anti-misoperation method, apparatus and system in the operation order dispatching provided by the embodiments, a pre-stored power grid equipment wiring diagram and a real-time-collected power grid operating state are displayed on a man-machine interaction interface, so that a dispatcher can execute the operation order according to the power grid equipment wiring diagram and the power grid operating state, and operation order mistake caused by dependence of memory of the dispatcher in operation order execution can be reduced; and after the dispatched operation order input from an operation order interface is received, anti-misoperation verification on the dispatched operation instruction also is performed, so that operation order mistake caused by manual operation order execution can be further reduced, and safety accidents in the power grid dispatching operation process can be reduced.