The invention provides a high transparent high thermoplastic chloroprene rubber pipe and a preparation method thereof. The high transparent high thermoplastic chloroprene rubber pipe is prepared from 40 to 60 parts by weight of chloroprene rubber, 40 to 60 parts by weight of nitrile rubber, 45 to 55 parts by weight of white carbon black, 0.5 to 1.5 parts by weight of high abrasion resistance furnace black, 0.5 to 1 part by weight of an anti-aging agent, 0.6 to 1.2 parts by weight of a liquid softener, 3 to 7 parts by weight of a promoter, 3 to 5 parts by weight of zinc oxide, 1 to 2 parts by weight of magnesium oxide, 50 to 60 parts by weight of stearic acid and 0.5 to 1.5 parts by weight of sulfur. The chloroprene rubber and the nitrile rubber are combined and produce synergism so that the high transparent high thermoplastic chloroprene rubber pipe has excellent wear resistance, tensile strength and tear strength. The preparation method realizes a low production cost, has simple processes and is easy to control.