The invention discloses a high-insulating cleaning agent for live cleaning of communication equipment. The high-insulating cleaning agent is prepared from, by weight, 65-80 parts of base oil, 10-15 parts of dichloromethane, 5-15 parts of fluorine-containing organic solvent, 0.1-0.5 part of fluorine-containing surfactant and 0.5-5 parts of silicone oil. By using the fluorine-containing organic solvent and the fluorine-containing surfactant at the same time, the requirements for high voltage withstanding value and good wettability can be met, the compatibility of a system can be improved, and high cleaning capacity under high voltage can be achieved.